Estrogen patch Rx of depression & Mini-Gastric Bypass
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Efficacy of estradiol topical patch in the treatment of symptoms of depression following mini-gastric bypass. Rutledge R, Dorghazi P, Peralgie C. The Centers for Excellence in Laparoscopic Obesity Surgery, Henderson, NV, USA. drr@clos.net BACKGROUND: Obesity is associated with elevated levels of estrogen. Gastric bypass causes rapid weight loss and decreased levels of estrogen. Patients after gastric bypass can suffer from anxiety and depression out of proportion to the surgical outcome. This study reports the efficacy of a short-term empiric trial of topical estradiol for the treatment of mild to moderate depression and anxiety following mini-gastric bypass (MGB) in women. METHODS: Postoperative MGB women were surveyed for the presence of depressive symptoms before and after MGB. The results of an empiric trial of transdermal patches of estradiol-17beta were assessed. Outcome measures were the self-reported efficacy of the patch. RESULTS: 711 women who had undergone MGB and had functioning e-mail addresses made up the study. 62% of patients reported depression prior to surgery. 156 patients (22%) reported depression after the operation. Patients treated with estradiol sustained antidepressant benefit. Depression is common in obese patients and remains a problem in a subset following the MGB operation. Transdermal estradiol replacement appears to be an effective treatment of symptoms of depression in women following MGB.
Tags: Antidepressant, Anxiety And Depression, Anxiety Depression, Bypass, Depression, Depression And Anxiety, Depression Anxiety, Depressive Symptoms, E Mail, Estrogen, Estrogen Patch, Henderson Nv, Mild Depression, MiniGastric, Moderate Depression, Nv Usa, Obese Patients, Obesity Surgery, Outcome Measures, patch, Rapid Weight Loss, Self Efficacy, Surgical Outcome, Symptoms Of Depression, Transdermal Patches
February 5th, 2010 at 9:04 am
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February 5th, 2010 at 9:25 am
I’ve had some friends say that they would walk for half an hour or so and that would help them relieve that feeling of being gassy. I can’t wait for my surgery…I’m a little scared, I hope you do really well!!! OCTOBER 1st BUDDDDYYYY!! Booyah
February 5th, 2010 at 9:26 am
OMG, the absolute wrong advice! What they need is Progesterone cream (U.S.P.-grade). They could also take “DIM” (Google it) to continue reducing estrogen levels, along with the progesterone would be best. In fact, just use DIM with progesterone and forget about the surgery.
June 9th, 2010 at 11:49 pm
I saw some clips on ET where he and his wife were blaming the Biggest Loser for not supporting him after his weight loss. His continued denial and excuse-making are what is making him gain weight. He won the show and knows what he needs to do to lose it again. He needs to quit blaming the show, his weight is his problem. It was disgusting seeing him blame others for his situation, which is his alone.